What are lamellar granules primarily composed of?

• A. Melanin and lipids
• B. Proteins and lipids
• C. Keratin and water
• D. Vitamin D and enzymes

Answer: (B)

Lamellar granules, also known as Odland bodies, are primarily composed of proteins and lipids. They play a critical role in the skin's barrier function. During the process of keratinization, these granules release their contents into the extracellular space, forming a lipid-rich layer that helps prevent water loss and protects against environmental factors. The lipids in lamellar granules contribute to the formation of the stratum corneum's hydrophobic barrier, while the proteins are involved in various structural and functional aspects of skin cells.

The combination of proteins and lipids ensures that the skin is not only resilient but also maintains hydration and provides an effective barrier against pathogens and physical damage. This is essential for overall skin health and homeostasis.